Research has shown a downside to grit. While grit can lead to persevering in obstacles, it can also lead to becoming too stubborn, causing a person to hold onto projects, goals, or relationships that are not worth holding onto.
In addition, people that are grittier than others tend to keep working at the loss of time, and even financial loss. 
While self-isolating, this can cause an individual to become even more discouraged if they fail at a project. It would be better for a person to focus on their mental health and self care while self-isolating from the coronavirus.